Project 2: Combustion-Generated EPFRs - Assessing Cardiovascular Risks of Exposure

Tammy Dugas (Leader), Kurt Varner, Ashlyn Harmon

Our project will examine the mechanisms underlying the cardiovascular responses and toxicities produced by inhalation of environmentally persistent free radicals (EPFRs), a unique type of pollutant formed during thermal treatment of organic materials and other hazardous substances commonly found at Superfund sites. Our studies will provide important new data linking exposure to EPFRs with the development and progression of cardiovascular disease. This information is critical for assessing risks to those living in proximity to sites using thermal treatment technologies to remediate Superfund or other hazardous wastes.